Dexilant 30 Mg 14 Capsules

Product Description

• Dexilant® is a dual-delayed-release proton-pump inhibitor (PPI) that contains dexlansoprazole, the R-enantiomer of lansoprazole.


• Each capsule houses two types of enteric-coated granules that dissolve at different pH levels, providing two peak plasma concentrations and up to 24-hour acid suppression in a single daily dose.

Indications:

• Healing of all grades of erosive esophagitis (EE)
  Maintenance of healed EE and relief of heartburn
  Symptomatic non-erosive GERD (gastroesophageal reflux disease)

How To Use

Administration Tips:

• Take with or without food, swallow whole; do not chew or crush.
  If swallowing is difficult, open the capsule and sprinkle intact granules onto 1 tablespoon of applesauce; swallow immediately without chewing .
  For nasogastric tube administration, follow official instructions provided by your pharmacist.

Warnings & Precautions:

• Gastric Malignancy: Symptom relief does not rule out gastric malignancy; investigate further if alarm symptoms (dysphagia, bleeding, weight loss) persist .


• Acute Interstitial Nephritis (AIN): Discontinue if AIN is suspected (fever, rash, worsening renal function).


• Vitamin B-12 Deficiency: Prolonged use (> 3 years) may reduce absorption; monitor levels in high-risk patients.


• Clostridioides difficile–associated diarrhea: Consider diagnosis in persistent diarrhea.


• Bone Fracture: Long-term, high-dose PPI therapy increases the risk of osteoporosis-related fractures of hip, wrist, or spine.


• Hypomagnesemia: Rare; monitor magnesium levels if symptoms (tremor, arrhythmias) appear.

Drug Interactions:

• Methotrexate – serum levels may rise; consider temporary withdrawal of Dexilant during high-dose methotrexate.
  Rilpivirine-containing products – contraindicated (reduces antiviral efficacy).
  Warfarin, clopidogrel, digoxin, tacrolimus, atazanavir – adjust doses or monitor INR, levels, or therapeutic effects .

Special Populations:

• Moderate hepatic impairment (Child-Pugh B): Do not exceed 30 mg/day.


• Severe hepatic impairment (Child-Pugh C): Not recommended .


• Pregnancy & Breastfeeding: Limited data; use only if clearly needed.

Ingredients:

• Active: dexlansoprazole 30 mg or 60 mg.
  Capsule shell & excipients: sugar spheres, magnesium carbonate, sucrose, low-substituted hydroxypropyl cellulose, hydroxypropyl cellulose, hypromellose, methacrylic acid copolymers, polyethylene glycol 8000, triethyl citrate, polysorbate 80, colloidal silicon dioxide, titanium dioxide, talc.

Capsule colors:

• 30 mg – blue & gray with “TAP 30” imprint


• 60 mg – blue with “TAP 60” imprint