Decapeptyl

Decapeptyl-CR 3.75 mg Injection (Refrigerator)

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Triptorelin 3 mg powder and solvent for suspension for injection (1 month)
Triptorelin 11.25 mg powder and solvent for suspension for injection (3-month)


What Triptorelin is used for:

Triptorelin belongs to a group of medicines called gonadotropin releasing hormone (GnRH) agonists. Triptorelin is similar to the gonadotropin releasing hormone which occurs naturally in your body. 
In men: Triptorelin lowers the levels of the hormone, testosterone. Both Triptorelin 3mg and 11.25mg are used to treat advanced prostate cancer.
In women: Triptorelin reduces estrogen levels. 
Triptorelin 3mg is used to treat:
Endometriosis - a condition in which the tissue that normally lines the uterus grows in other places.
Uterine fibroids - abnormal benign growth of cells in your uterus.
Female infertility.
Early stage hormone responsive breast cancer in pre-menopausal women who have received chemotherapy. Triptorelin is used together with hormone medicines. You will also be asked to take: 
o A medicine called ‘tamoxifen’ – you will be asked to take this medicine if you are at high risk of the cancer coming back or
o An ‘aromatase inhibitor’ medicine such as ‘exemestane’ – you will have treatment with Triptorelin for at least 6 to 8 weeks before you start taking this medicine.
Triptorelin 11.25 mg is used to treat:
Endometriosis - a condition in which the tissue that normally lines the uterus grows in other places.
In children: Triptorelin 11.25mg is used to treat puberty that occurs at a very young age (Precocious Puberty).


Do not take Triptorelin if:

If you are allergic to triptorelin or similar types of drugs (other gonadotropin releasing hormone (GnRH) agonists) or any of the other ingredients of this medicine.
If you are a man and your prostate cancer has spread to your spine or if the tumor is pressing on your spine. 


Warnings and precautions:

Tell your doctor about all of your health conditions, including, if you have:
depressed mood 
anything wrong with you that affects your bones, such as osteoporosis. 
diabetes. 
have any heart or blood vessel conditions. 
A benign tumor of the pituitary gland that you were unaware of, this may be discovered during treatment with Triptorelin.


Possible side effects:
Like All medicines, this medicine can cause side effects although not everybody gets them. In rare cases you may experience a severe allergic reaction. Tell your doctor immediately if you develop symptoms such as swallowing or breathing problems, a rash, swelling of your lips, face, throat or tongue.


MEN: Many of the side effects are expected, due to the change in the level of testosterone in your body. These effects include hot flushes, impotence and decreased libido. Other side effects include: weakness, excessive sweating, back pain, pins and needles sensation in the legs, reduced libido, impotence, nausea, dry mouth, pain, bruising, redness and swelling when injected, muscle and bone pain, pain in the arms/legs, oedema, lower abdominal pain, high blood pressure, allergic reaction, increase in weight, dizziness, headache, loss of libido, depression and mood changes.


WOMEN: Many of the side effects are expected to be due to the change in the level of estrogens in your body. Other side effects include: mood swings, difficulty sleeping, breast disorder, ovarian hyperstimulation syndrome, pain during or after sexual intercourse, painful periods, genital bleeding, pelvic pain, dryness of the vagina, excessive sweating, acne, oily skin, hot flushes, breast pain, muscle cramps, painful joints, weight gain, feeling sick, depression, nervousness, abdominal pain or discomfort, pain, bruising, redness and swelling at injection site, swelling and tenderness, allergic reaction, pain in the arms and legs, dizziness.


CHILDREN: Side effects include vaginal bleeding which may occur in girls in the first month of treatment, pain in abdomen, bruising, redness and swelling at injection site, headache, hot flushes, weight gain, acne, hypersensitivity reactions.
Other medicines and Triptorelin
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. 
Triptorelin might interfere with some medicines used to treat heart rhythm problems or might increase the risk of heart rhythm problems when used with some other drugs used for pain relief and part of drug addiction detoxification, certain antibiotics and drugs used for serious mental illnesses. 
Drugs which increase the level of a hormone called prolactin may react with Triptorelin. Many different kinds of drugs may increase prolactin levels.


How to use Triptorelin:
MEN:

Triptorelin 3mg:
Triptorelin 3mg will be injected into a muscle, usually your bottom, by a doctor or nurse. 
You will normally receive an injection once every 28 days.
Triptorelin 11.25mg:
Triptorelin 11.25mg will be injected into a muscle, usually your bottom, or subcutaneously, by a doctor or nurse. You will normally receive an injection once every 3 months.
WOMEN:

Triptorelin 3mg:
Triptorelin 3mg will be injected into a muscle, usually your bottom, by a doctor or nurse.
You will normally receive one injection every 28 days. This injection should be given in the first 5 days of your menstrual cycle.
If you are being treated for uterine fibroids you should be treated for at least 3 months.
If you are being treated for infertility you will receive 1 injection per course of IVF. You should not need to be treated for more than 6 months.
If you are being treated for breast cancer, the recommended dose of Triptorelin 3mg is one injection into a muscle, every 4 weeks (28 days). Treatment may last up to five years.
Triptorelin 3mg is used together with a medicine called ‘tamoxifen’ or an ‘aromatase inhibitor’, such as ‘exemestane’. If you need to take an ‘aromatase inhibitor’, you will have treatment with Triptorelin 3mg for at least 6 to 8 weeks before you start taking it. You will be receiving at least 2 injections of Triptorelin 3mg (with an interval of 4 weeks between injections) before you start taking it.
Triptorelin 11.25mg:
Triptorelin 11.25mg will be injected into a muscle, usually your bottom, by a doctor or nurse. You will normally receive two injections, the second one three months after the first. The first injection will be given in the first five days of your period. You should not need to be treated for more than 6 months.
CHILDREN:

Triptorelin 11.25mg:
Triptorelin 11.25mg will be injected into a muscle, usually your bottom, by a doctor or nurse.
You will normally receive an injection once every 3 months. Your doctor will decide when treatment should be stopped (normally when you are about 12 if you are a girl and about 13-14 if you are a boy).


How to store Triptorelin:

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the vial and on the outer box. The expiry date refers to the last day of the month.
Once opened/reconstituted, immediate use is recommended.
This medicine should not be stored above 25°C.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

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  • Manufacturer: Decapeptyl
  • Ingredients: Triptorelin