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Dexilant

Dexilant 30 mg 28 capsules

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Dexlansoprazole 30 mg delayed-release capsules

What dexlansoprazole is used for

It is a proton pump inhibitor (PPI).
The delayed-release capsules are indicated in adults for: 
Healing of all grades of erosive esophagitis (EE)
Maintaining healing of EE and relief of heartburn
Treating heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD)
The SoluTab delayed-release orally disintegrating tablets are indicated in adults for:
Maintaining healing of EE and relief of heartburn
Treating heartburn associated with GERD

Do not use dexlansoprazole
Patients with known hypersensitivity to any component of the formulation
Patients receiving rilpivirine-containing products

Warnings and precautions

Gastric Malignancy: Symptomatic response with dexlansoprazole does not preclude the presence of gastric malignancy
Acute Interstitial Nephritis: Observed in patients taking PPIs
Cyanocobalamin (Vitamin B-12) Deficiency: Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin
Clostridium difficile Associated Diarrhea: PPI therapy may be associated with increased risk
Bone Fracture: Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine
Hypomagnesemia: Reported rarely with prolonged treatment with PPIs
Interactions with Diagnostic Investigations for Neuroendocrine Tumors: Increases in intragastric pH may result in hypergastrinemia and enterochromaffin-like cell hyperplasia and increased chromogranin A levels which may interfere with diagnostic investigations for neuroendocrine tumors
Interaction with Methotrexate: Concomitant use with PPIs may elevate and/or prolong serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal.

Possible side effects
Stop using the product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing. Stop using the product if you develop hives or itching of the face or body. 

Other medicines and dexlansoprazole

Tell your doctor or pharmacist if you are taking:
Antiretrovirals
Warfarin
Methotrexate
Digoxin
Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenoloate mofetil, ketoconazole/itraconazole)
Tacrolimus
CYP2C19 or CYP3A4 Inhibitors
CYP2C19 or CYP3A4 Inducers

How to use dexlansoprazole
Recommended Adult Dosage:
Two 30 mg SoluTab are not interchangeable with one 60 mg capsule
Dexlansoprazole capsules
Healing of EE: 60 mg once daily for up to 8 weeks
Maintenance of healed EE: 30 mg once daily for up to 6 months
Symptomatic non-erosive GERD: 30 mg once daily for 4 weeks
Dexlansoprazole SoluTab
Maintenance of healed EE: 30 mg once daily for up to 6 months
Symptomatic non-erosive GERD: 30 mg once daily for 4 weeks
Administration Instructions:
Dexlansoprazole capsules
Take without regard to food
Swallow whole; do not chew
Dexlansoprazole SoluTab
Take at least 30 minutes before a meal

How to store dexlansoprazole

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.
Store between 20°C to 25°C. Store in the original container. Keep the container tightly closed.
Do not use if you notice any deterioration or damage to the outer packaging.
Do not throw away any medicines via wastewater or household waste.

Read More
  • Manufacturer: Dexilant
  • Ingredients: Dexlansoprazole (Granule Ll)