This medicine works to reduce your cholesterol in two ways.
The active ingredient ezetimibe reduces the cholesterol absorbed in your digestive tract.
The active ingredient simvastatin belonging to the class of “statins” inhibits the production of the cholesterol your body makes by itself.

Do not use Ezetimibe and simvastatin:

you are allergic (hypersensitive) to ezetimibe, simvastatin, or any of the other ingredients of this medicine
you currently have liver problems,
you are pregnant or breast-feeding,
you are taking medicine(s) with one or more than one of the following active ingredients:
itraconazole, ketoconazole, posaconazole, or voriconazole (used to treat fungal infections),
erythromycin, clarithromycin, or telithromycin (used to treat infections),
HIV protease inhibitors such as indinavir, nelfinavir, ritonavir, and saquinavir (HIV protease inhibitors are used to treat HIV infections),
boceprevir or telaprevir (used to treat hepatitis C virus infections),
nefazodone (used to treat depression),
cobicistat,
gemfibrozil (used to lower cholesterol),
ciclosporin (often used in organ transplant patients),
danazol (a man-made hormone used to treat endometriosis, a condition in which the lining of the uterus grows outside the uterus).
you are taking or have taken, in the last 7 days, a medicine called fusidic acid.

Warnings and precautions:

Tell your doctor:
about all your medical conditions including allergies,
if you drink large amounts of alcohol or have ever had liver disease. It may not be right for you,
if you are due to have an operation. You may need to stop taking tablets for a short time,
if you are Asian, because a different dose may be applicable to you.

Possible side effects:

Stop using the product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing.
Stop using the product if you develop hives or itching of the face or body.

Other medicines and Ezetimibe and simvastatin:

Tell your doctor if you are taking, have recently taken or might take any other medicine(s) with any of the following active ingredients
If you need to take oral fusidic acid to treat a bacterial infection you will need to temporarily stop using this medicine
ciclosporin
danazol
medicines with an active ingredient like itraconazole, ketoconazole, fluconazole, posaconazole, or voriconazole (used to treat fungal infections)
fibrates with active ingredients like gemfibrozil and bezafibrate
erythromycin, clarithromycin, or telithromycin
HIV protease inhibitors such as indinavir, nelfinavir, ritonavir, and saquinavir
Hepatitis C antiviral agents such as boceprevir, telaprevir, elbasvir, or grazoprevir
nefazodone (used to treat depression)
medicines with the active ingredient cobicistat
amiodarone
verapamil, diltiazem, or amlodipine
lomitapide
daptomycin
large amounts (1 gram or more each day) of niacin or nicotinic acid (also used to lower cholesterol)
colchicine

How to use Ezetimibe and simvastatin:

Adults: The dose is 1 tablet by mouth once a day.
Use in adolescents (10 to 17 years of age): The dose is 1 tablet by mouth once a day (a maximum dose of 10 mg/40 mg once daily must not be exceeded).
The 10 mg/80 mg dose is only recommended for adult patients with very high cholesterol levels and at high risk of heart disease problems who have not reached their cholesterol goal on lower doses.
Take in the evening. You can take it with or without food.

How to store Ezetimibe and simvastatin:

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton or container after [EXP].
Do not store tablets above 30°C.
Store in the original package in order to protect from moisture and light.

Inegy 20 mg/10 mg Tablet 28pcs