Paquix 5mg 60 Tablets
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Paquix contains the active substance apixaban and belongs to a group of medicines called anticoagulants. This medicine helps to prevent blood dots from forming by blocking Factor Xa which is an important component of blood clotting.
Paquix is used in adults:
- To prevent blood clots (deep vein thrombosis [DVT]) from forming after hip or knee replacement operations. After an operation to the hip or knee you may be at a higher risk of developing blood clots in your leg veins. This can cause the legs to swell, with or without pain. If a blood clot travels from your leg to your lungs, it can block blood flow causing breathlessness, with or without chest pain. This condition (pulmonary embolism) can be life-threatening and requires immediate medical attention.
- To prevent a blood clot from forming in the heart in patients with an irregular heart beat (atrial fibrillation) and at least one additional risk factor. Blood dots may break off and travel to the brain and lead to a stock or to other organs and prevent normal blood flow to that organ (also known as a systemic embolism). A stroke can be life-threatening and require immediate medical attention.
- To treat blood dots in the veins of your legs (deep vein thrombosis) and in the blood vessels of your lungs (pulmonary embolism), and to prevent blood clots from re-occurring in the blood vessels of your legs and\or lugs.
How to use:Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor, pharmacist or nurse if you are not sure.
To prevent a blood clot from forming in the heart in patients with an irregular heartbeat and at least one additional risk factor.
- The recommended dose is one tablet of Paquix 5 mg twice a day.
- The recommended dose is one tablet of Paquix 2.5 mg twice a day if,
- You have severely reduced kidney function.
- Two or more of the following apply to you: Your blood test results suggest poor kidney function (value of serum creatinine is 1.5 mg/dL (133 micromole\L) or greater)
- You are 80 years old or older.
- Your weight is 60 kg or lower.
- The recommended dose is one tablet twice a day, for example, one in the morning and one in the evening. Try to take the tablets at the same times every day to have the best treatment effect.
Swallow the tablet with a drink of water. Paquix can be taken with or without food.
Your doctor will decide how long you must continue treatment.
For preventing blood clots from re-occurring following completion of 6 months of treatment; The recommended dose is one tablet of Paquix 2.5 mg twice a day for example one in the morning and one in the evening. Try to take the tablets at the same times every day to have the best treatment effect.
Caution & Warnings:
a. Do not take Paquix if:
- You are allergic to apixaban or any of the other ingredients of this medicine.
- You are bleeding excessively.
- You have a disease in an organ of the body that increase the risk of serious bleeding (such as an active or a recent ulcer at your stomach or bowel. recent bleeding in your brain).
- You have a liver disease which leads to increased risk of bleeding (hepatic coagulopathy).
- You are taking medicines to prevent blood clotting (e.g. warfarin. rivaroxaban, dabigatran or heparin), except when changing anticoagulant treatment or while having a venous or arterial line and you get heparin through this line to keep it open.
b. Take special care with Paquix
Before taking Paquix, tell your doctor about all of your medical conditions, including if you have any the following:
- An increased risk of bleeding, such as.
- bleeding disorders, including conditions resulting in reduced platelet activity
- very high blood pressure, not controlled by medical treatment
- you are older than 75 years
- you weigh 60 kg or less
- A severe kidney disease or if you are on dialysis.
- A liver problem or a history of liver problems Paquix will be used with caution in patients with signs of altered liver function.
- If you have a prosthetic heart valve.
- If your doctor determines that your blood pressure is unstable or another treatment or surgical procedure to remove the blood dot from your lungs is planned.
If you need to have surgery or a procedure which may cause bleeding, your doctor might ask you to temporarily stop taking this medicine for a short while, If you are not sure whether a procedure may cause bleeding ask your doctor.
c. Children and adolescents
Paquix is not recommended in children and adolescents under 18 years of age.
d. Taking other medicines, herbal or dietary supplements
Tell your doctor, pharmacist or nurse it you are taking, have recently taken or might take any other medicines.
Some medicines may increase the effects of Paquix and some may decrease its effects. Your doctor will decide, if you should be treated with Paquix when taking these medicines and how closely you should be monitored.
The following medicines may increase the effects of Paquix and increase the chance for unwanted bleeding:
- Some medicines for fungal infections (e.g. ketoconazole, etc.).
- Some antiviral medicines for HIV\AIDS (e.g., Ritonavir).
- Other medicines that are used to reduce blood clotting (e.g., enoxaparin, etc.).
- Anti-inflammatory or pain medicines (e.g. aspirin or naproxen). Especially, if you are older than 75 years and are taking aspirin. You may have an increased change of bleeding.
- Medicines for high blood pressure or heart problems (e.g.. diltiazem).
The following medicines may reduce the ability of Paquix to help prevent blood clots from forming:
- Medicines to prevent epilepsy or seizures (e.g. phenytoin. etc.).
- St John’s Wort (a herbal supplement used for depression).
- Medicines to treat tuberculosis or other infections (e.g. rifampicin)
e. Pregnancy and breast-feeding
PregnancyIf you are pregnant or breast-feeding, think you may be pregnant ae planning to have a baby, ask your doctor, pharmacist or nurse for advice before taking this medicine. The effects of Paquix on pregnancy and the unborn child are not known. You should not take Paquix if you are pregnant. Contact your doctor immediately if you become pregnant while taking Paquix.
LactationIt is not known if Paquix passes into human breast mills. Ask your doctor, pharmacist or nurse for advice before taking this medicine while breast-feeding. They will advise you to either stop breast-feeding or to stop/not start taking Paquix.
f. Driving and using machines
Paquix has not been shown to impair your ability to drive or use machine.
g. Important information about some of the ingredients:
Paquix contains lactose (a type of sugar). It you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
Apixaban 5 mg.
Lactose, Microcrystalline Cellulose, Croscarmellose Sodium, Sodium Lauryl Sulphate, Magnesium Stearate, Opadry White OYL & Yellow Iron Oxide.
- Manufacturer: Paquix
- Product form: Tablets
- Ingredients: Apixaban