Epipen Adult 0.3Mg

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Epinephrine (Adrenaline) solution for injection   

What Epinephrine is and what it is used for:

Adrenaline (Epinephrine) belongs to a class of drugs called sympathomimetic agents. 

Adrenaline injection can be used for the emergency treatment of severe allergic reactions.

What you need to know before you use Epinephrine:

You should not be given Adrenaline Injection if you are:

allergic to adrenaline, or to any of the other ingredients of this medicine 

Adrenaline injection should not be used in areas such as fingers, toes, ears, nose, genitalia or buttocks, as the blood supply to these areas might become inadequate

Warnings and precautions:

Talk to your doctor or pharmacist or nurse before using Adrenaline Injection if: 

you are elderly

you suffer from any heart problem, particularly if it affects the heart rate or if you suffer from chest pain

you have problems with your brain e.g. stroke, brain damage or blood vessel disease

you have an overactive thyroid, diabetes or glaucoma (high pressure in the eye)

you have phaeochromocytoma (a tumour on the adrenal gland) 

you have low blood levels of potassium or high blood levels of calcium.

you have a tumour on your prostate gland or kidney disease

you are in shock or have lost a lot of blood

you are going to have a surgery under general anaesthesia

you are suffering from high blood pressure

you have atherosclerosis which is a narrowing and hardening of the body’s blood vessels (your doctor will advise you).

Other medicines and Epinephrine:

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.

A large number of drugs can interact with Adrenaline Injection which can significantly alter their effects. These drugs include: 

monoamine oxidase inhibitors (MAOI) or tricyclic antidepressants such as imipramine, amitriptyline, both used for depression

cardiac glycosides such as digoxin, used for heart failure

guanethidine, used for the rapid control of blood pressure

diuretics (“water tablets”) such as hydrochlorothiazide, furosemide

inhaled general anaesthetics, such as halothane

medicines to raise or lower your blood pressure including betablockers, e.g. propranolol, atenolol, bisoprolol, phentolamine

anti-diabetic drugs like insulin or oral hypoglycaemic agents (e.g. glipizide)

aminophylline and theophylline (medicines to help you breathe)

corticosteroids (medicines used to treat inflammatory conditions in your body such as asthma or arthritis)

antihistamines (for example: diphenhydramine), used for the treatment of allergies

medicines used to treat mental illness like chlorpromazine, pericyazine or fluphenazine

medicines used to treat an underactive thyroid gland

oxytocin (used to induce labour at term and to control bleeding after delivery)

any cough or cold remedies (sympathomimetics).

How to use Epinephrine:

Your doctor will give Adrenaline Injection to you into a muscle (Intramuscular - IM), however, in emergencies your doctor may give you a diluted injection into your vein (intravenous - IV). 

Adrenaline injection must NOT be given in areas such as fingers, toes, ears, nose, genitalia or buttocks, as the blood supply to these areas might become inadequate.

If repeated injections are required, your doctor will change the site of injection. It will be administered by a trained healthcare professional. 

Your doctor will decide the most suitable dosage and route of administration for your particular case according to your age and physical circumstances. 


The usual dose is 0.5ml. If necessary, this dose may be repeated several times at 5-minute intervals.


There are no specific dose regimens for adrenaline injection in elderly patients, however adrenaline should be used with great caution.


The following doses of Adrenaline Solution for Injection are recommended:

Over 12 years: 0.5 mg IM (0.5ml 1mg/ml solution), 0.3 mg IM (0.3ml 1mg/ml solution) if the child is small or pre-pubertal)

6 - 12 years: 0.3 mg IM (0.3ml 1mg/ml solution)

6 months – 6 years: 0.15 mg IM (0.15ml 1mg/ml solution)

Under 6 months: 0.01mg/kg IM (0.01ml/kg 1mg/ml solution)

Possible side effects:

If you experience any of these following side effects, stop using this medicine and report to a doctor immediately:

allergic reactions although serious allergic reactions are rare

any sudden wheeziness, difficulty in breathing

swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body).

How to store Epinephrine:

Keep all medicines out of the sight and reach of children.

Your doctor, nurse or paramedic will check that the expiry date on the label has not been passed before administering Adrenaline Injection to you. The expiry date refers to the last day of the month.

You should not be given the Adrenaline Injection if you notice it has been used or shows signs of visible damage. 

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

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