Solu-Cortef 250 mg Vial 2 ml

Hydrocortisone 250 mg powder and solvent for solution for injection
What Hydrocortisone is used for:

• Hydrocortisone is a used for the following:


• When your adrenal gland is not working properly (e.g. adrenal insufficiency).


• To treat shock (serious condition when your body is not getting enough blood flow).


• To treat certain inflammatory conditions.

Do not take Hydrocortisone:

• If you’re allergic to the active substance or any other component of this medicine.


• If you have an untreated fungal infection such as thrush.


• If you have any other untreated infections.


• If you recently had or are about to have a vaccination.

Warnings and precautions:

• Talk to your doctor about all your medical conditions before taking this medicine including:


• If you have a traumatic brain injury or stroke.


• If you have heart problems or had a recent heart attack.


• If you have a high blood pressure (hypertension).


• If you have any type of infection including viral infections| tuberculosis and HIV.


• If you have a severe depression or manic depression.


• If you have diabetes.


• If you have Cushing’s disease.


• If you have seizures (fits).


• If you have eye conditions such as glaucoma or cataract.


• If you have fluid retention in your body (edema).


• If you have an under-active thyroid gland (hypothyroidism).


• If you have Myasthenia Gravis or other muscle problems.


• If you have liver or kidney problems.


• If you have pancreatitis (inflamed pancreas).


• If you have stomach ulcers.


• If you have osteoporosis (thinning bones).


• If you have a spreading (metastatic) cancer.


• If you have or may have a condition called pheochromocytoma.


• Long term therapy of corticosteroids may increase the risk of having infections.


• If you develop signs of infection while taking this medicine contact your doctor.


• If you have been taking this medicine for a long time| do not stop suddenly. Talk to your doctor.

Possible side effects:

• Stop using this product and seek immediate medical help if you develop rash; hives; itching; red| swollen| blistered| or peeling skin; wheezing; tightness in the chest or throat; trouble breathing| swallowing| or talking; unusual hoarseness; or swelling of the mouth| face| lips| tongue| or throat.


• Serious side effects:


• Mental problems: depression and mood swings


• Pancreatitis (inflamed pancreas)


• Infections


• Blood clots


• Seizures (fits)


• Eye problems


• Stomach ulcers

Other medicines and Hydrocortisone:

• Tell your doctor about all the medicines you are taking.


• Always tell your healthcare providers that you are taking Hydrocortisone.


• Hydrocortisone interacts with a lot of medicine including:


• Anticoagulants


• Certain antibiotics


• Certain antivirals


• Certain antifungals


• Medicines used for diabetes


• Medicines used for tuberculosis


• Non steroidal anti-inflammatory drugs


• Aspirin


• Medicines used for epilepsy


• Estrogens


• Digoxin


• Diuretics (water tablets)


• Medicines used after transplant


• Vaccines

How to take Hydrocortisone:

• The injection is given as a shot in the muscle or into a vein. Your doctor or nurse will inject you.


• Take the tablets with food.


• The dose and route of administration will depend on your case.


• For the injection| the dosing range is usually between 250 – 500 mg.


• For the tablets| the usual dosing is 10 –40 mg per day but can be higher in emergencies.

How to store Hydrocortisone:

• Store at room temperature below 77°F (25°C).


• Keep this medicine out of reach of children.


• Do not use this medicine after the expiry date stated on the package.


• The expiry date refers to the last day of that month.

*Dosage form and route of administration of Hydrocortisone 250 mg powder and solvent for solution for injection| 10 mg tablets and 20 mg tablets should be prescribed according to therapeutic indication and disease severity of each individual patient.