Letara Letrozole 2.5 mg - 30 Tablets

Product Overview:

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  Letara (Letrozole) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

  
  


• This Product Contains 30 Tablets

Key Features:

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  Letrozole is commonly used to treat certain types of breast cancer, including hormone receptor-positive breast cancer, in women after menopause.

  
  


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  Letrozole may also be used for other conditions as determined by your healthcare provider.

  
  

How it Works:

• Letrozole belongs to a class of medicines called aromatase inhibitors. It works by blocking an enzyme called aromatase that helps produce estrogen in the body. By lowering the amount of estrogen, letrozole can help prevent the growth of tumors that rely on estrogen to grow.

Benefits:

• Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer


• Extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy


• First-line treatment of advanced breast cancer in postmenopausal women with hormone receptor positive or unknown locally advanced or metastatic breast cancer; second-line treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy

Directions for Use:

• Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.


• You may take letrozole with or without food.


• You will need frequent medical tests, and your bone mineral density may also need to be checked.

Active Ingredients:

• Letrozole 2.5 mg

Side Effects:

Severe Allergic Reactions. Letrozole may cause allergic reactions, which can be serious. Stop taking letrozole and get help right away if you have any of the following symptoms of a serious allergic reaction.

• Breathing problems or wheezing


• Racing heart


• Fever or general ill feeling


• Swollen lymph nodes


• Swelling of the face, lips, mouth, tongue, or throat


• Trouble swallowing or throat tightness


• Itching, skin rash, or pale red bumps on the skin called hives


• Nausea or vomiting


• Dizziness, feeling lightheaded, or fainting


• Stomach cramps


• Joint pain


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  Weak Bones. Taking letrozole for a long time may cause your bones to become weaker, leading to reduced bone density (osteopenia). It may also cause a more serious condition called osteoporosis, which can cause bones to break (fracture) more easily. If you take letrozole, your healthcare provider may monitor your bone density. Tell your healthcare provider if you break a bone, and get a bone mineral density test if one is ordered for you.

  
  

Common side effects may include:

• Hot flashes, flushing, or increased sweating


• Lack of energy and weakness


• Pain, including bone pain, headache, and joint pain


• High cholesterol (see below)


• Fluid retention


• Dizziness

Cautions & Warnings:

• Talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, skin rash, swelling of the face or neck, decreased blood pressure and dizziness.


• This medication may affect your bone density. Your doctor may recommend bone density monitoring.


• This medication may increase your total cholesterol. Your doctor may recommend cholesterol monitoring.


• This medication may cause fatigue, drowsiness and dizziness. Do not drive or use machinery if you are not feeling well. Possible side effects of Letrozole : Possible side effects of Letrozole include allergic reaction, hot flashes, joint pain, flushing, weakness, edema, headache, dizziness, elevated cholesterol levels, sweating and bone pain.

Pregnancy Warnings:

• letrozole is for use only in women who can no longer get pregnant. Letrozole can harm an unborn baby. Do not use if you are pregnant. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of letrozole. Tell your doctor if you think you may be pregnant.

Breastfeeding Warnings:

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  You should not breastfeed while you are using letrozole and for at least 3 weeks after your last dose.

  
  

Storage:

• Letrozole should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place.

FAQ:

• Q: Does letrozole interact with other medicines (drug interactions)?
  A: Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.In particular, make sure that you discuss if you are using any of the following before taking letrozole.Tamoxifen, a medicine that is used to treat and prevent breast cancer
  An estrogen medicine, such as hormone replacement, certain birth control pills, and estrogen creams, rings, or suppositories


• Q: What should I do if I miss a dose of letrozole?
  A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.


• Q: What other drugs will affect letrozole?
  A: Other drugs may affect letrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.


• Q: How long do letrozole side effects last?
  A: Most side effects of letrozole are mild and temporary, lasting only a few days or weeks until your body gets used to taking the medication. Some other side effects of letrozole take a few months to develop and tend to persist long term until you stop taking letrozole. The half-life of letrozole is 2 days, so once you stop taking letrozole, you might continue to experience side effects for about a week to 10 days after your last dose.


• Q: What happens when you stop taking letrozole?
  A: When you stop taking letrozole, side effects such as swelling, cough, hot flashes, and nausea, should improve within a week or 10 days. Some, such as high cholesterol, bone loss, and hair thinning may take many months to resolve. As long as you have taken it for at least 5 years, then letrozole should continue to reduce the risk of breast cancer coming back for many years after you stop taking it. Letrozole is usually taken for 5 years, but may be recommended for up to 10 years depending on individual circumstances.