- Age Range: Adults
- Brand: Cooper Pharma
- Concentration: 300 mg
- Gender: Unisex
- Key Health Benefit: Nerve support
- Main Ingredient: Alpha Lipoic Acid
- Quantity: 30 Capsules
Product Overview
Theomax Plus is a premium dietary supplement formulated to support nerve health, metabolic balance, and cardiovascular protection. It combines three clinically proven ingredients—Alpha Lipoic Acid, Vitamin B1, and Vitamin B12—to address the complex needs of diabetic patients, individuals with neuropathy, and those seeking enhanced antioxidant defense.
Key Ingredients & Biological Actions
Ingredient | Biological Role |
Alpha Lipoic Acid (Thioctic Acid) 300 mg | - Endogenous fatty acid which is a potent antioxidant that neutralizes free radicals - Enhances glucose metabolism via glycolysis - Improves insulin sensitivity and lowers blood sugar - Protects nerves and cardiovascular tissues through significant decrease of Pro inflammatory mediators such as IL6, TNFa and C-reactive protein |
Vitamin B1 (Thiamine) 40mg | - Maintains nerve function Supports energy production - Prevents diabetic complications |
Vitamin B12 (Cobalamin) (250 mcg) | -Essential for nerve regeneration - Reduces neuropathic pain and numbness - Supports red blood cell formation |
Indications & Usages
Theomax Plus is recommended for:
- Diabetic patients: Helps regulate blood glucose and reduce neuropathic symptoms such as burning, tingling, and numbness.
- Cardiovascular patients: Enhances circulation, protects heart muscle, and reduces oxidative stress.
- Neuropathy sufferers: Alleviates nerve pain and supports nerve repair.
- Elderly individuals: Offers neuroprotective and cardioprotective benefits to counter age-related degeneration.
- Post-injury recovery: Supports nerve healing and reduces inflammation.
Pathogenesis-Oriented Treatment Strategy
The International Expert Consensus Recommendations on the screening, diagnosis, and management of Diabetic Sensorimotor Polyneuropathy (DSPN) highlights that DSPN is not just a symptom-driven condition—it stems from oxidative stress, microvascular dysfunction, and metabolic imbalance. Therefore, treatments should target these underlying mechanisms.
- Alpha Lipoic Acid (ALA) is one of the few agents that directly address these root causes:
- Antioxidant action: Neutralizes reactive oxygen species (ROS), reducing oxidative damage to nerves.
- Improves endoneurial blood flow: Enhances microcirculation within nerve tissues.
- Modulates glucose metabolism: Improves insulin sensitivity and reduces hyperglycemia-induced damage.
- Vitamin B1 (Thiamine) and Vitamin B12 (Cobalamin):
- Support nerve conduction and myelin sheath integrity.
- Prevent and reverse deficiency-related neuropathy, which is common in diabetic patients.
- Vitamin B12 also plays a role in homocysteine regulation, reducing cardiovascular risk.
Additional Patient Benefits of Theomax Plus
Whole-Body Antioxidant Protection
- Alpha Lipoic Acid (ALA) is both water- and fat-soluble, allowing it to penetrate all tissues—including the brain, nerves, liver, and heart.
- It recycles other antioxidants like Vitamin C and E, amplifying the body’s defense against oxidative stress.
Support for Metabolic Syndrome & Insulin Resistance
- ALA improves insulin sensitivity, helping patients with prediabetes or metabolic syndrome manage blood sugar more effectively.
- May reduce triglycerides and LDL cholesterol, contributing to better lipid profiles.
Neuroprotection Beyond Diabetes
- Emerging evidence suggests ALA may help protect against neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
- Supports optic nerve health, potentially benefiting patients with glaucoma or age-related vision decline.
Post-Injury & Post-Surgical Recovery
- ALA’s anti-inflammatory and nerve-regenerating properties make it useful in nerve injury recovery, post-surgical healing, and even sports-related rehabilitation.
Weight Management Support
- Some studies show modest weight loss effects (0.5–2 kg) with ALA supplementation, especially in overweight individuals.
Ideal for Elderly Patients
- Addresses common deficiencies in Vitamin B1 and B12, which are prevalent in older adults due to reduced absorption.
- Supports cognitive clarity, nerve function, and cardiovascular resilience—without known toxicity at recommended doses.
Clinical Evidence & Guideline Support for Theomax Plus
1. Systematic Review on Alpha Lipoic Acid & B Vitamins in Diabetic Neuropathy
A 2022 protocol published in BMJ Open outlines a systematic review and meta-analysis of randomized controlled trials evaluating the effectiveness of Alpha Lipoic Acid (ALA) and Vitamin B complex in treating diabetic neuropathy. The review emphasizes their role in reducing inflammation, improving lipid profiles, and enhancing glucose metabolism.
“ALA and Vitamin B12 have been regarded as components that can reduce markers of inflammation and oxidative stress in diabetic neuropathy.” — BMJ Open, 2022
2. ADA-Endorsed Review on B Vitamins in Diabetic Peripheral Neuropathy (DPN)
A 2019 systematic review presented at the American Diabetes Association (ADA) conference analyzed 51 studies involving over 4,600 patients. It found that Vitamin B1, B6, and B12, alone or in combination with ALA, significantly improved neuropathy-related symptoms and nerve function compared to placebo and active controls.
“B vitamins had a positive effect on neurophysiological symptoms and/or functions in 38 studies.” — ADA, 2019
3- The SYDNEY Trial and other studies cited in the consensus show that ALA (600 mg/day) significantly improves Total Symptom Score (TSS) in DSPN patients, reducing pain, numbness, and paresthesia.
4- A 2022 review in BMJ Open supports the combination of ALA + Vitamin B complex as effective in reducing inflammatory markers, improving lipid profiles, and enhancing nerve functio
4. Comparative Study in Egyptian Diabetic Patients
A clinical study published in Walsh Medical Media compared Vitamin B complex + ALA versus Vitamin B alone in Egyptian Type 2 diabetic patients. The combination therapy showed superior outcomes in delaying or reversing diabetic polyneuropathy symptoms.
Guideline Highlights
- European Federation of Neurological Societies (EFNS) recommends ALA for symptomatic treatment of diabetic polyneuropathy due to its antioxidant and neuroprotective properties.
- American Academy of Neurology (AAN) supports the use of Vitamin B12 in managing neuropathic pain and preventing deficiency-related nerve damage.
- WHO and NIH recognize Thiamine (B1) as essential in glucose metabolism and nerve function, especially in diabetic populations.
Clinical Implication for Theomax Plus
Theomax Plus embodies this consensus-driven approach:
- Combines ALA + B1 + B12 in a single, high-quality formulation
- Targets oxidative stress, nerve dysfunction, and metabolic imbalance
- Suitable for early intervention, adjunct therapy, and long-term support
Safety Profile
Safety in Special Populations
Elderly Patients: The combination is well-tolerated and beneficial for age-related nerve degeneration and cardiovascular support. No dose adjustments are typically required unless renal impairment is present.
- Safe and beneficial for age-related nerve and heart health. No known contraindications when used as directed.
- Pregnancy: While Alpha Lipoic Acid and B vitamins are generally considered safe, pregnant women should consult their healthcare provider before use.
- No teratogenic effects have been reported in standard doses, and B12 is often prescribed during pregnancy to support fetal neural development.
- Drug Interactions: No major interactions reported, but patients on insulin or hypoglycemic agents should monitor blood sugar levels closely.
Product Details
- Form: Vegetable Capsules
- Pack Size: 30 Capsules
- Recommended Dose: 300–1200 mg/day based on medical advice
- Administration: Take on an empty stomach with water, preferably while sitting upright
Theomax plus is a premium European brand of Cooper pharma.
SFDA registration: Food Registration System
Barcode: 8410885095190
Hs code: 29362900
Product Details:
- Quantity: 30 Capsules
- Age Range: Adults
- Brand: Cooper Pharma
- Concentration: 300 mg
- Gender: Unisex
- Key Health Benefit: Nerve support
- Main Ingredient: Alpha Lipoic Acid
Genuine brands
Temperature Controlled
Secure Payment
- Age Range: Adults
- Brand: Cooper Pharma
- Concentration: 300 mg
- Gender: Unisex
- Key Health Benefit: Nerve support
- Main Ingredient: Alpha Lipoic Acid
- Quantity: 30 Capsules
Genuine brands
Temperature Controlled
Secure Payment
About Product
Product Overview
Theomax Plus is a premium dietary supplement formulated to support nerve health, metabolic balance, and cardiovascular protection. It combines three clinically proven ingredients—Alpha Lipoic Acid, Vitamin B1, and Vitamin B12—to address the complex needs of diabetic patients, individuals with neuropathy, and those seeking enhanced antioxidant defense.
Key Ingredients & Biological Actions
Ingredient | Biological Role |
Alpha Lipoic Acid (Thioctic Acid) 300 mg | - Endogenous fatty acid which is a potent antioxidant that neutralizes free radicals - Enhances glucose metabolism via glycolysis - Improves insulin sensitivity and lowers blood sugar - Protects nerves and cardiovascular tissues through significant decrease of Pro inflammatory mediators such as IL6, TNFa and C-reactive protein |
Vitamin B1 (Thiamine) 40mg | - Maintains nerve function Supports energy production - Prevents diabetic complications |
Vitamin B12 (Cobalamin) (250 mcg) | -Essential for nerve regeneration - Reduces neuropathic pain and numbness - Supports red blood cell formation |
Indications & Usages
Theomax Plus is recommended for:
- Diabetic patients: Helps regulate blood glucose and reduce neuropathic symptoms such as burning, tingling, and numbness.
- Cardiovascular patients: Enhances circulation, protects heart muscle, and reduces oxidative stress.
- Neuropathy sufferers: Alleviates nerve pain and supports nerve repair.
- Elderly individuals: Offers neuroprotective and cardioprotective benefits to counter age-related degeneration.
- Post-injury recovery: Supports nerve healing and reduces inflammation.
Pathogenesis-Oriented Treatment Strategy
The International Expert Consensus Recommendations on the screening, diagnosis, and management of Diabetic Sensorimotor Polyneuropathy (DSPN) highlights that DSPN is not just a symptom-driven condition—it stems from oxidative stress, microvascular dysfunction, and metabolic imbalance. Therefore, treatments should target these underlying mechanisms.
- Alpha Lipoic Acid (ALA) is one of the few agents that directly address these root causes:
- Antioxidant action: Neutralizes reactive oxygen species (ROS), reducing oxidative damage to nerves.
- Improves endoneurial blood flow: Enhances microcirculation within nerve tissues.
- Modulates glucose metabolism: Improves insulin sensitivity and reduces hyperglycemia-induced damage.
- Vitamin B1 (Thiamine) and Vitamin B12 (Cobalamin):
- Support nerve conduction and myelin sheath integrity.
- Prevent and reverse deficiency-related neuropathy, which is common in diabetic patients.
- Vitamin B12 also plays a role in homocysteine regulation, reducing cardiovascular risk.
Additional Patient Benefits of Theomax Plus
Whole-Body Antioxidant Protection
- Alpha Lipoic Acid (ALA) is both water- and fat-soluble, allowing it to penetrate all tissues—including the brain, nerves, liver, and heart.
- It recycles other antioxidants like Vitamin C and E, amplifying the body’s defense against oxidative stress.
Support for Metabolic Syndrome & Insulin Resistance
- ALA improves insulin sensitivity, helping patients with prediabetes or metabolic syndrome manage blood sugar more effectively.
- May reduce triglycerides and LDL cholesterol, contributing to better lipid profiles.
Neuroprotection Beyond Diabetes
- Emerging evidence suggests ALA may help protect against neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
- Supports optic nerve health, potentially benefiting patients with glaucoma or age-related vision decline.
Post-Injury & Post-Surgical Recovery
- ALA’s anti-inflammatory and nerve-regenerating properties make it useful in nerve injury recovery, post-surgical healing, and even sports-related rehabilitation.
Weight Management Support
- Some studies show modest weight loss effects (0.5–2 kg) with ALA supplementation, especially in overweight individuals.
Ideal for Elderly Patients
- Addresses common deficiencies in Vitamin B1 and B12, which are prevalent in older adults due to reduced absorption.
- Supports cognitive clarity, nerve function, and cardiovascular resilience—without known toxicity at recommended doses.
Clinical Evidence & Guideline Support for Theomax Plus
1. Systematic Review on Alpha Lipoic Acid & B Vitamins in Diabetic Neuropathy
A 2022 protocol published in BMJ Open outlines a systematic review and meta-analysis of randomized controlled trials evaluating the effectiveness of Alpha Lipoic Acid (ALA) and Vitamin B complex in treating diabetic neuropathy. The review emphasizes their role in reducing inflammation, improving lipid profiles, and enhancing glucose metabolism.
“ALA and Vitamin B12 have been regarded as components that can reduce markers of inflammation and oxidative stress in diabetic neuropathy.” — BMJ Open, 2022
2. ADA-Endorsed Review on B Vitamins in Diabetic Peripheral Neuropathy (DPN)
A 2019 systematic review presented at the American Diabetes Association (ADA) conference analyzed 51 studies involving over 4,600 patients. It found that Vitamin B1, B6, and B12, alone or in combination with ALA, significantly improved neuropathy-related symptoms and nerve function compared to placebo and active controls.
“B vitamins had a positive effect on neurophysiological symptoms and/or functions in 38 studies.” — ADA, 2019
3- The SYDNEY Trial and other studies cited in the consensus show that ALA (600 mg/day) significantly improves Total Symptom Score (TSS) in DSPN patients, reducing pain, numbness, and paresthesia.
4- A 2022 review in BMJ Open supports the combination of ALA + Vitamin B complex as effective in reducing inflammatory markers, improving lipid profiles, and enhancing nerve functio
4. Comparative Study in Egyptian Diabetic Patients
A clinical study published in Walsh Medical Media compared Vitamin B complex + ALA versus Vitamin B alone in Egyptian Type 2 diabetic patients. The combination therapy showed superior outcomes in delaying or reversing diabetic polyneuropathy symptoms.
Guideline Highlights
- European Federation of Neurological Societies (EFNS) recommends ALA for symptomatic treatment of diabetic polyneuropathy due to its antioxidant and neuroprotective properties.
- American Academy of Neurology (AAN) supports the use of Vitamin B12 in managing neuropathic pain and preventing deficiency-related nerve damage.
- WHO and NIH recognize Thiamine (B1) as essential in glucose metabolism and nerve function, especially in diabetic populations.
Clinical Implication for Theomax Plus
Theomax Plus embodies this consensus-driven approach:
- Combines ALA + B1 + B12 in a single, high-quality formulation
- Targets oxidative stress, nerve dysfunction, and metabolic imbalance
- Suitable for early intervention, adjunct therapy, and long-term support
Safety Profile
Safety in Special Populations
Elderly Patients: The combination is well-tolerated and beneficial for age-related nerve degeneration and cardiovascular support. No dose adjustments are typically required unless renal impairment is present.
- Safe and beneficial for age-related nerve and heart health. No known contraindications when used as directed.
- Pregnancy: While Alpha Lipoic Acid and B vitamins are generally considered safe, pregnant women should consult their healthcare provider before use.
- No teratogenic effects have been reported in standard doses, and B12 is often prescribed during pregnancy to support fetal neural development.
- Drug Interactions: No major interactions reported, but patients on insulin or hypoglycemic agents should monitor blood sugar levels closely.
Product Details
- Form: Vegetable Capsules
- Pack Size: 30 Capsules
- Recommended Dose: 300–1200 mg/day based on medical advice
- Administration: Take on an empty stomach with water, preferably while sitting upright
Theomax plus is a premium European brand of Cooper pharma.
SFDA registration: Food Registration System
Barcode: 8410885095190
Hs code: 29362900
Product Details:
- Quantity: 30 Capsules
- Age Range: Adults
- Brand: Cooper Pharma
- Concentration: 300 mg
- Gender: Unisex
- Key Health Benefit: Nerve support
- Main Ingredient: Alpha Lipoic Acid