Gizlan HCT Irbesartan/Hydrochlorothiazide 300 mg/25 mg – 30 Tablets

Product Overview:

• Gizlan (Irbesartan and hydrochlorothiazide) tablets are indicated for the treatment of hypertension.


• Irbesartan and hydrochlorothiazide tablets may be used in patients whose blood pressure is not adequately controlled on monotherapy.
  Irbesartan and hydrochlorothiazide tablets may also be used as initial therapy in patients who are likely to need multiple drugs to achieve their blood pressure goals.


• The choice of irbesartan and hydrochlorothiazide tablets as initial therapy for hypertension should be based on an assessment of potential benefits and risks.
  Patients with stage 2 (moderate or severe) hypertension are at relatively high risk for cardiovascular events (such as strokes, heart attacks, and heart failure), kidney failure, and vision problems, so prompt treatment is clinically relevant. The decision to use a combination as initial therapy should be individualized and may be shaped by considerations such as the baseline blood pressure, the target goal, and the incremental likelihood of achieving goal with a combination compared with monotherapy.


• This product contains 30 capsules

Key Features:

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  Hydrochlorothiazide is a diuretic (water pill). Irbesartan is an angiotensin II receptor blocker (sometimes called an ARB blocker). 

  
  


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  Hydrochlorothiazide and irbesartan is a combination medicine used to treat high blood pressure (hypertension).

  
  

How it Works:

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  The medicine works by reducing the risk of strokes and myocardial infarction (heart attack), thereby treating hypertension (high blood pressure).

  
  

Benefits:

• Irbesartan and hydrochlorothiazide tablets may also be used as initial therapy in patients who are likely to need multiple drugs to achieve their blood pressure goals.

Directions for Use:

• Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.


• You may take this medicine with or without food.


• Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Active Ingredients:

• Hydrochlorothiazide 25 mg, Irbesartan 300 mg

Side Effects:

• Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.


• In rare cases, hydrochlorothiazide and irbesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Common side effects of hydrochlorothiazide and irbesartan may include:

• dizziness;


• muscle or joint pain; or


• feeling tired.

Cautions & Warnings:

• You should not use this medicine if you are unable to urinate, or if you are allergic to sulfa drugs.


• Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.


• If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine).

Pregnancy Warnings:

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  Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

  
  

Breastfeeding Warnings:

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  You should not breastfeed while using this medicine.

  
  

Storage:

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  Store at room temperature away from moisture and heat.

  
  

FAQ:

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  Q. What is Irbesartan+Hydrochlorothiazide?
  A:Irbesartan+Hydrochlorothiazide is a combination of two medicines that helps keep the blood pressure under control. The medicine works by reducing the risk of strokes and myocardial infarction (heart attack), thereby treating hypertension (high blood pressure).

  
  


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  Q. How should I take Irbesartan+Hydrochlorothiazide?
  A:You should take Irbesartan+Hydrochlorothiazide exactly as directed by your doctor. It is for oral use and is usually taken once a day. You should take it with plenty of water, with or without food. It is recommended that you take this medicine at the same time every day.

  
  


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  Q. What if I forget to take a dose of Irbesartan+Hydrochlorothiazide?
  A:If you have missed a dose of Irbesartan+Hydrochlorothiazide, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule instead of taking the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

  
  


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  Q. How long does Irbesartan+Hydrochlorothiazide take to start working?
  A:Irbesartan+Hydrochlorothiazide may take about 2 weeks to show a visible reduction in blood pressure. Full benefits of Irbesartan+Hydrochlorothiazide may take a little longer, about 4 weeks. However, if you are worried or have any concerns, contact your doctor.

  
  


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  Q. What is the most important information I should know about A:Irbesartan+Hydrochlorothiazide?
  It is important for you to know that this medicine can cause harm or death to your unborn baby. Therefore, if you are planning a pregnancy or have become pregnant, consult your doctor right away. Your doctor may switch you to a different medicine to treat your high blood pressure.