Ikotref Hydrocortisone Sodium Succinate 100 mg - 1 Vial

Product Overview:

• Ikotref Hydrocortisone Sodium Succinate 100 mg - 1 Vial


• Hydrocortisone sodium succinate for injection, USP is an anti-inflammatory glucocorticoid that contains hydrocortisone sodium succinate as the active ingredient. Hydrocortisone sodium succinate for injection is available for intravenous or intramuscular administration.

Key Features:

• 100 mg Plain—Single-dose vial containing hydrocortisone sodium succinate equivalent to 100 mg hydrocortisone, 0.8 mg monobasic sodium phosphate anhydrous and 8.73 mg dibasic sodium phosphate anhydrous. Hydrocortisone sodium succinate for injection 100 mg plain does not contain diluent

How it Works:

• Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.

Benefits:

• Corticosteroid-responsive dermatoses, hypersensitivity reactions such as, angioedema, status asthmaticus, Soft tissue inflammation, Joint inflammations, Primary or secondary adrenocortical insufficiency, Acute adrenocortical insufficiency, Shock unresponsive to conventional therapy, Congenital adrenal hyperplasia, Hypercalcemia associated with cancer, Nonsuppurative thyroiditis, Rheumatic Disorders, Dermatologic Diseases, (Allergic States, Severe seborrheic dermatitis, Severe psoriasis, Pemphigus, Severe erythema multiforme), Control of severe or incapacitating allergic conditions, (Bronchial asthma, Contact dermatitis, Atopic dermatitis, Serum sickness, Seasonal or perennial allergic rhinitis, Drug hypersensitivity reactions, Urticarial transfusion reactions,


• Acute noninfectious laryngeal edema), Ophthalmic Diseases, (Herpes zoster ophthalmicus, Iritis, iridocyclitis, Chorioretinitis, Diffuse posterior uveitis and choroiditis, Optic neuritis), Gastrointestinal Diseases, Fulminating or disseminated pulmonary tuberculosis, when used concurrently with appropriate antituberculous chemotherapy, Loeffler's syndrome, Aspiration pneumonitis, Hematologic Disorders, (Acquired, autoimmune hemolytic anemia, Idiopathic thrombocytopenic purpura in adults, Secondary thrombocytopenia, Erythroblastopenia), Neoplastic Diseases, (Leukemias and lymphomas in adults, Acute leukemia of childhood), Edematous States, Acute exacerbations of multiple sclerosis

Active Ingredients:

• HYDROCORTISONE

Side Effects:

• Sodium and fluid retention. Potassium and calcium depletion. Muscle wasting, weakness, osteoporosis. GI disturbances and bleeding. Increased appetite and delayed wound healing. Bruising, striae, hirsutism, acne, flushing. Raised intracranial pressure, headache, depression, psychosis, menstrual irregularities. Hyperglycaemia, glycosuria, DM, obesity, moon-face, buffalo hump. Suppression of pituitary-adrenocortical system. Growth retardation in childn (prolonged therapy). Increased susceptibility for infection. Topical use: Dermal atrophy, local irritation, folliculitis, hypertrichosis. Inhaled corticosteroids: May cause hoarseness, candidiasis of mouth and throat. Topical application to the eye: Can produce corneal ulcers, raised IOP and reduced visual function. Intralesional injection: Local hypopigmentation of deeply pigmented skin. Intra-articular injection: Joint damage, fibrosis esp in load bearing joints.

Cautions & Warnings:

• Serious Neurologic Adverse Reactions with Epidural Administration


• Serious neurologic events, some resulting in death, have been reported with epidural injection of corticosteroids. Specific events reported include, but are not limited to, spinal cord infarction, paraplegia, quadriplegia, cortical blindness, and stroke. These serious neurologic events have been reported with and without use of fluoroscopy. The safety and effectiveness of epidural administration of corticosteroids have not been established, and corticosteroids are not approved for this use.

Storage:

• Store unreconstituted product at 20º to 25ºC (68º to 77ºF); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature].


• Store reconstituted and/or further diluted solution at controlled room temperature 20°C to 25°C (68°F to 77°F) and protect from light. Use the reconstituted and/or further diluted solution within 12 hours of preparation. Use reconstituted/diluted solution only if it is clear. If kept at controlled room temperature unused reconstituted and/or further diluted solution should be discarded after 12 hours post preparation. If kept under refrigerated conditions, unused reconstituted and/or further diluted solution should be used in no more than 24 hours and any unused portion should be discarded after that time.

FAQ:

• Q:How should I store IKOTREF 100mg?


• A:IKOTREF 100mg should be stored according to the instructions provided by TABUK PHARMACEUTICAL MANUFACTURING CO. In general, it is recommended to store IKOTREF 100mg in a cool, dry place, away from direct sunlight and out of the reach of children.

• Q:How long should I continue taking IKOTREF 100mg?


• A:The duration of treatment with IKOTREF 100mg may vary depending on the condition being treated and the guidance of your healthcare provider. It is important to follow the prescribed treatment plan and continue taking IKOTREF 100mg for the recommended duration, even if your symptoms improve. If you have any concerns or questions about the duration of treatment, consult your healthcare provider.

• Q:Can I consume alcohol while taking IKOTREF 100mg?


• A:It is important to check with your healthcare provider or read the medication label for specific instructions regarding alcohol consumption while taking IKOTREF 100mg. Some medications, including IKOTREF 100mg, may have interactions with alcohol that can reduce effectiveness, increase side effects, or pose other risks to your health. It is best to follow the guidance provided by your healthcare professional.

• Q:What should I do if I miss a dose of IKOTREF 100mg?


• A:If you miss a dose of IKOTREF 100mg, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.

• Q:Can I take IKOTREF 100mg if I am pregnant or breastfeeding?


• A:It is important to consult your healthcare provider before taking IKOTREF 100mg if you are pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your specific situation. Please note that the safety and suitability of IKOTREF 100mg during pregnancy or breastfeeding may depend on the active substance [Active Substance], concentration 100 mg / Vial