Verzenio Abemaciclib 200 mg - 14 Tablets

Product Overview:

• Verzenio (Abemaciclib) 14 Tablets is used to treat certain types of breast cancer. It works by blocking the action of proteins that help cancer cells grow and multiply

How it works?:

• Verzenio is a type of medicine called a kinase inhibitor. It blocks the action of cyclin-dependent kinases 4 and 6 (CDK4 and CDK6). CDK4 and CDK6 help cancer cells to grow and multiply. Verenzio blocks the activity of CDK4 and CDK6 to help stop cancer cells from growing and multiplying and to make tumors shrink in size.

Benefits:

• Verzenio (abemaciclib) is commonly used for treating breast cancer that is hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative. It treats early breast cancer as well as cancer that is advanced or has spread to other parts of the body (metastatic). It is usually given in combination with other medicines, but it may also be used alone.


• It may also be used for breast cancer that is advanced or has spread and has a specific gene change called an ESR1 mutation, in people whose cancer kept growing after at least one hormone therapy.

Directions for Use:

• Abemaciclib is usually taken 2 times a day, at about the same times every day.


• Take with or without food.


• Swallow whole. Do not chew, crush, or split the tablet. Do not take a tablet that is broken, cracked, or damaged.


• If you vomit after taking abemaciclib, do not take another dose. Take your next dose at your regular time.

Active Ingredient(s):

• Abemaciclib 200 mg

Side Effects:

• Diarrhea (see below)


• Infections


• Blood disorders (see below)


• Tiredness


• Stomach pain


• Nausea and vomiting


• Decreased appetite


• Headache


• Hair loss

Cautions & Warnings:

• May cause diarrhea.


• May cause liver damage.


• Use with caution in patients with a history of liver disease or who are taking medications that may affect the liver.

Pregnancy Warnings:

• Verzenio may cause harm to a fetus. Tell your health care provider right away if you are pregnant, think you might be pregnant, or plan to become pregnant. You must not be pregnant before starting Verzenio. If you can become pregnant, use effective birth control during treatment with Verzenio and for 3 weeks after your last dose.

Breastfeeding Warnings:

• Do not undergo treatment with Verzenio while you are breastfeeding and for 3 weeks after your last dose. It is not known if Verzenio passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed.

Storage:

• Verenzio should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place.

FAQ:

• Q. What should I do if I miss a dose of Verzenio?


• A. If you miss a dose, do not take the missed dose. Instead, take your next dose as scheduled. Do not take 2 doses of Verzenio at the same time to make up for a missed dose.


• Q. What should I tell my health care provider before using Verzenio?


• A. Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Verzenio is right for you.


• Q. Does Verzenio interact with foods or drinks?


• A. Grapefruit can increase the amount of Verzenio in your body and increase your risk of side effects. It is important to avoid eating grapefruit or drinking any grapefruit juice while taking Verzenio.


• It is unknown if drinking alcohol will affect Verzenio, but heavy drinking can slow your immune response and make it harder for your body to fight cance


• Q. Does Verzenio interact with other medicines (drug interactions)?


• A. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.


• In particular, make sure you discuss if you are taking ketoconazole, which is a medicine used for fungal infections, before taking Verzenio.


• Many other medicines may alter the blood levels of Verzenio. Tell your health care provider about all medicines that you take or have recently taken.


• This may not be a complete list of medicines that can interact with Verzenio. Always check with your health care provider.