Xitamet Sitagliptin 50 mg / Metformin 850 mg - 56 Tablets

Product Overview:

• Xitamet (Metformin and sitagliptin) 56 Tablets is a combination medicine used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus (not for type 1 diabetes).


• Metformin and sitagliptin may also be used for purposes not listed in this medication guide.

Key Features:

• It helps to control blood sugar levels very effectively


• It works through two different mechanisms to improve the body's response to insulin.


• It reduces glucose production in the liver and improves sugar absorption in cells.


• A convenient dosage combining two medications in one tablet for easy adherence to treatment.


• A box containing 56 tablet

How it works?:

• Sitagliptin/metformin works in several ways to help keep your blood sugar levels from getting too high. It increases the levels of natural hormones in your body to lower blood sugar by increasing insulin levels, especially after meals. Insulin is a hormone that helps your body use sugar as a source of energy. Sitagliptin/metformin also decreases the amount of sugar your body absorbs from things you eat and drink, reduces the amount of sugar that your liver makes, and helps your body’s own insulin work better. 

• Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

• sitagliptin 50 mg + metformin 850 mg

• Call your doctor at once if you have any of these serious side effects: severe or ongoing pain in your joints; a severe skin reaction-- itching, blisters, breakdown of the outer layer of skin; kidney problems or symptoms of heart failure--swelling, urinating less, rapid weight gain, feeling tired or short of breath; or severely low blood sugar--extreme weakness, confusion, tremors, sweating, fast heartbeats, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions).


• Common side effects of metformin and sitagliptin may include:


• Low blood sugar (if you also use insulin or another oral diabetes medication);


• Upset stomach, indigestion, gas, diarrhea, nausea, vomiting;


• headache, weakness; or


• Cold symptoms such as runny or stuffy nose, sneezing, sore throat.

• You should not use metformin and sitagliptin if you have severe kidney disease or metabolic acidosis (including diabetic ketoacidosis).


• You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

Pregnancy Warnings:

• It is not known if or how sitagliptin/metformin could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. If you get pregnant, talk to your healthcare provider about how to control your blood sugar while you are pregnant.

Breastfeeding Warnings:

• It is unknown if sitagliptin/metformin passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take sitagliptin/metformin while breastfeeding.

• Sitagliptin/metformin should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place. Read and follow any specific storage recommendations that come with your medicine, such as storing in the original bottle or throwing tablets away after a specified amount of time from when the bottle was first opened. Ask your pharmacist if you have any questions about storing your sitagliptin/metformin.

• Q. What happens if I miss a dose?


• A. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.


• Q. Does sitagliptin/metformin interact with foods or drinks?


• A. There are no known interactions between sitagliptin/metformin and foods or drinks.
• Alcohol can increase the risk of lactic acidosis. See the Side Effects section for more details. It is unknown if drinking alcohol will affect sitagliptin/metformin in other ways, but alcohol may affect blood sugar levels in people with diabetes. This may interfere with the effect of sitagliptin/metformin. It is best to limit the amount of alcohol you drink.


• Q. What should I avoid while taking metformin and sitagliptin?


• A. Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.